| 產(chǎn)品編號 | bs-12896R-APC |
| 英文名稱1 | Rabbit Anti-TAF13/APC Conjugated antibody |
| 中文名稱 | APC標(biāo)記的轉(zhuǎn)錄起始因子TFIID亞基13抗體 |
| 別 名 | MGC22425; TAF(II)18; taf13; TAF13 RNA polymerase II, TATA box binding protein (TBP) associated factor, 18kDa; TAF13_HUMAN; TAF2K; TAFII 18; TAFII-18; TAFII18; Transcription initiation factor TFIID 18 kDa subunit; Transcription initiation factor TFIID subunit 13. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Orangutan) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 14kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TAF13 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit associated with a subset of TFIID complexes. This subunit interacts with TBP and with two other small subunits of TFIID, TAF10 and TAF11. There is a pseudogene located on chromosome 6. [provided by RefSeq, Jul 2008] Function: TFIID beta-specific TAFII. Subunit: TFIID is composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFs). Interacts with TBP, and more strongly with TAF10 and TAF11. Subcellular Location: Nucleus. Similarity: Belongs to the TAF13 family. Contains 1 histone-fold domain. Database links: Entrez Gene: 6884 Human Entrez Gene: 99730 Mouse Entrez Gene: 100172778 Orangutan Omim: 600774 Human SwissProt: Q15543 Human SwissProt: P61216 Mouse SwissProt: Q5R9W6 Orangutan Unigene: 632426 Human Unigene: 24431 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
