| 產(chǎn)品編號(hào) | bs-18684R-BF488 |
| 英文名稱1 | Rabbit Anti-MARVELD2/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的MARVEL蛋白家族D2抗體 |
| 別 名 | DFNB49; FLJ30532; MARVD2; MARVEL (membrane associating) domain containing 2; MARVEL domain containing 2; MARVEL domain containing protein 2; MARVELD 2; MARVELD2; MRVLDC2; Tric; Tricellulin. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說(shuō) 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞膜蛋白 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, Monkey, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Bat) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 64kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MARVELD2 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: The protein encoded by this gene is a membrane protein found at the tight junctions between epithelial cells. The encoded protein helps establish epithelial barriers such as those in the organ of Corti, where these barriers are required for normal hearing. Defects in this gene are a cause of deafness autosomal recessive type 49 (DFNB49). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] Function: Plays a role in the formation of the epithelial barriers. The separation of the endolymphatic and perilymphatic spaces of the organ of Corti from one another by epithelial barriers is required for normal hearing. Subcellular Location: Cell membrane; Multi-pass membrane protein. Cell junction, tight junction. Note=Found at tricellular contacts. DISEASE: Deafness, autosomal recessive, 49 (DFNB49) [MIM:610153]: A form of non-syndromic sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. Note: The disease is caused by mutations affecting the gene represented in this entry. Similarity: Contains 1 MARVEL domain. Database links: Entrez Gene: 461831 Chimpanzee Entrez Gene: 101128096 Gorilla Entrez Gene: 153562 Human Entrez Gene: 100173144 Orangutan Omim: 610572 Human SwissProt: Q8N4S9 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
