| 產(chǎn)品編號(hào) | bs-16337R-BF555 |
| 英文名稱1 | Rabbit Anti-GSTA2/BF555 Conjugated antibody |
| 中文名稱 | BF555標(biāo)記的谷胱甘肽S轉(zhuǎn)移酶2抗體 |
| 別 名 | EC 2.5.1.18; Glutathione S transferase 2; Glutathione S transferase A2; Glutathione S-alkyltransferase A2; Glutathione S-aralkyltransferase A2; Glutathione S-aryltransferase A2; Glutathione S-transferase alpha 2; Glutathione S-transferase GT41A; Glutathione S-transferase Ya-2; Glutathione S-transferase, alpha 2 (Yc2); GST 1b-1b; GST A2-2; GSTA2_HUMAN; GST class alpha member 2; GST gamma; GST Ya2; GST, class alpha, 2; GST2; Gst2-2; GSTA2 2; GSTA2-2; Gstc-2; Gstc2; GTA2; GTH2; HA subunit 2; Liver GST2; MGC10525; OTTHUMP00000017883; S-(hydroxyalkyl)glutathione lyase A2. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 新陳代謝 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Monkey, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 26kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GSTA2 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation. [provided by RefSeq, Jul 2008] Function: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, which are located in a cluster on chromosome 6, are highly related and encode enzymes with glutathione peroxidase activity that function in the detoxification of lipid peroxidation products. Reactive electrophiles produced by oxidative metabolism have been linked to a number of degenerative diseases including Parkinson's disease, Alzheimer's disease, cataract formation, and atherosclerosis. Subunit: Homodimer or heterodimer of GSTA1 and GSTA2. Subcellular Location: Cytoplasmic Tissue Specificity: Liver. Similarity: Belongs to the GST superfamily. Alpha family. Contains 1 GST C-terminal domain. Contains 1 GST N-terminal domain. Database links: Entrez Gene: 2939 Human GenBank: NM_000846.4 Human Omim: 138360 Human SwissProt: P09210 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
