| 產(chǎn)品編號(hào) | bs-14083R-Gold |
| 英文名稱(chēng)1 | Rabbit Anti-CSDE1/Gold Conjugated antibody |
| 中文名稱(chēng) | 膠體金標(biāo)記的RNA冷休克域結(jié)合蛋白E1抗體 |
| 別 名 | Cold shock domain containing E1 RNA binding; Cold shock domain containing protein E1; Cold shock domain-containing protein E1; Csde1; CSDE1_HUMAN; D1S155E; DKFZp779B0247; DKFZp779J1455; FLJ26882; N-ras upstream gene protein; NRAS related; Nras upstream gene protein; NRU; Protein UNR; RP5 1000E10.3; UNR; UNR protein; Upstream of NRAS. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢價(jià) |
| 說(shuō) 明 書(shū) | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 細(xì)胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 結(jié)合蛋白 表觀遺傳學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, ) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 89kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CSDE1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: UNR is a 798 amino acid protein that localizes to the cytoplasm and contains nine CDS (cold shock) domains. Existing as a component of the multi-protein autoregulatory ribonucleoprotein complex (ARC), UNR functions as an RNA-binding protein that is required for the initiation of rhinovirus RNA translation and is thought to be involved in translationally coupled mRNA turnover. UNR is expressed as two isoforms, designated long and short, and shares over 98% amino acid identity with its rat counterpart, suggesting a conserved role between species. The gene encoding UNR maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Function: RNA-binding protein. Required for internal initiation of translation of human rhinovirus RNA. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Subcellular Location: Cytoplasm. Similarity: Contains 9 CSD (cold-shock) domains. Database links: Entrez Gene: 7812 Human Entrez Gene: 229663 Mouse Omim: 191510 Human SwissProt: O75534 Human SwissProt: Q91W50 Mouse Unigene: 69855 Human Unigene: 277713 Mouse Unigene: 3562 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
