| 產(chǎn)品編號 | bs-9375R-Gold |
| 英文名稱1 | Rabbit Anti-MYCBP2/Gold Conjugated antibody |
| 中文名稱 | 膠體金標(biāo)記的MYC結(jié)合蛋白2抗體 |
| 別 名 | Pam/highwire/rpm-1 protein; Phr1; MYC binding protein 2; PAM; Pam, highwire, rpm 1; Protein associated with Myc; Probable E3 ubiquitin-protein ligase MYCBP2; Myc-binding protein 2; Pam/highwire/rpm-1 protein; Protein associated with Myc; MYCB2_HUMAN. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 細胞生物 信號轉(zhuǎn)導(dǎo) 細胞周期蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Horse, Sheep, ) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 510kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MYCBP2 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: MYCBP2 belongs to the highwire family. It is a probable E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. MYCBP2 may function as a facilitator or regulator of transcriptional activation by MYC and have a role during synaptogenesis. There are two different isoforms. Function: Probable E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. May function as a facilitator or regulator of transcriptional activation by MYC. May have a role during synaptogenesis. Subunit: Interacts with MYC. Interacts with TSC2 (tuberin) when TSC2 is in complex with TSC1 (hamartin). Interacts with FBXO45. Subcellular Location: Nuclear Tissue Specificity: Expressed in all tissues examined, expression is exceptionally abundant in brain and thymus. Colocalizes with TSC1 and TSC2 along the neurites and in the growth cones. Colocalized with TSC1 in one of the filopodial extensions at the tip of a growth cone. Similarity: Belongs to the highwire family. Contains 1 B box-type zinc finger. Contains 1 DOC domain. Contains 1 filamin repeat. Contains 5 RCC1 repeats. Contains 1 RING-type zinc finger. Database links: Entrez Gene: 23077 Human Entrez Gene: 105689 Mouse Omim: 610392 Human SwissProt: O75592 Human SwissProt: Q7TPH6 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
