| 產(chǎn)品編號 | bs-0299R-Cy5 |
| 英文名稱1 | Rabbit Anti-Adenylate Kinase 1/Cy5 Conjugated antibody |
| 中文名稱 | Cy5標(biāo)記的腺苷酸激酶-1抗體 |
| 別 名 | Adenylate kinase isoenzyme 1; Adenylate kinase soluble; AK 1; AK1; AK-1; ATP AMP transphosphorylase; Myokinase; KAD1_HUMAN; ATP-AMP transphosphorylase 1. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 腫瘤 心血管 信號轉(zhuǎn)導(dǎo) 新陳代謝 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Goat, Monkey, ) |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 21kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Adenylate Kinase 1 (131-194aa) |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme. [provided by RefSeq, Jul 2008]. Function: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Small ubiquitous enzyme involved in energy metabolism and nucleotide synthesis that is essential for maintenance and cell growth. Subunit: Monomer. Subcellular Location: Cytoplasm. DISEASE: Defects in AK1 are the cause of hemolytic anemia due to adenylate kinase deficiency (HAAKD) [MIM:612631]. Similarity: Belongs to the adenylate kinase family. Database links: Entrez Gene: 203 Human Entrez Gene: 11636 Mouse Omim: 103000 Human SwissProt: P00568 Human SwissProt: Q9R0Y5 Mouse Unigene: 175473 Human Unigene: 29189 Mouse Unigene: 79537 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. AK1存在于人類紅細(xì)胞上及某些組織中的具有遺傳多態(tài)性的同工酶, 腺苷酸激酶催化 ATP，AMP 和 ADP 的轉(zhuǎn)化，它是維持各種腺苷酸平衡的關(guān)鍵酶。因此，腺苷酸激酶就成為調(diào)控腺苷酸庫大小的靶標(biāo)分子。 |
