| 產(chǎn)品編號(hào) | bs-7797R-Gold |
| 英文名稱(chēng)1 | Rabbit Anti-DUSP13/Gold Conjugated antibody |
| 中文名稱(chēng) | 膠體金標(biāo)記的雙特異性磷酸酶13抗體 |
| 別 名 | BEDP; Branching enzyme interacting dual specificity protein phosphatase; Dual specificity phosphatase 13; Dual specificity phosphatase SKRP4; DUSP13A; DUSP13B; FLJ32450; MDSP; Muscle restricted dual specificity phosphatase; SKRP4; Testis and skeletal muscle specific DSP; TMDP; DUS13_HUMAN. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢(xún)價(jià) |
| 說(shuō) 明 書(shū) | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 細(xì)胞生物 發(fā)育生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞周期蛋白 激酶和磷酸酶 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Cow, Sheep, ) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 22kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DUSP13 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: Members of the protein-tyrosine phosphatase superfamilycooperate with protein kinases to regulate cell proliferation anddifferentiation. This superfamily is separated into two familiesbased on the substrate that is dephosphorylated. One family, thedual specificity phosphatases (DSPs) acts on both phosphotyrosineand phosphoserine/threonine residues. This gene encodes differentbut related DSP proteins through the use of non-overlapping openreading frames, alternate splicing, and presumed differenttranscription promoters. Expression of the distinct proteins fromthis gene has been found to be tissue specific and the proteins maybe involved in postnatal development of specific tissues. A proteinencoded by the upstream ORF was found in skeletal muscle, whereasthe encoded protein from the downstream ORF was found only intestis. In mouse, a similar pattern of expression was found.Multiple alternatively spliced transcript variants were described,but the full-length sequence of only some were determined.[provided by RefSeq, Jul 2008]. Function: May be involved in the regulation of meiosis and/ordifferentiation of testicular germ cells during spermatogenesis.Exhibits intrinsic phosphatase activity towards bothphospho-seryl/threonyl and -tyrosyl residues of myelin basicprotein, with similar specific activities in vitro. Tissue Specificity: Most abundantly expressed in the testis. Alsofound in the skeletal muscle. Testis-specific (at protein level). Similarity: Belongs to the protein-tyrosine phosphatase family.Non-receptor class dual specificity subfamily. Contains 1 tyrosine-protein phosphatase domain. Database links: UniProtKB/Swiss-Prot: Q9UII6.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
