| 產(chǎn)品編號 | bs-7659R-AP |
| 英文名稱1 | Rabbit Anti-DATF1/AP Conjugated antibody |
| 中文名稱 | 堿性磷酸酶（AP）標(biāo)記的死亡相關(guān)轉(zhuǎn)錄因子1抗體 |
| 別 名 | BYE 1; BYE1; C20orf158; DATF 1; Death associated transcription factor 1; Death inducer obliterator 1; DIDO 1; DIDO 2; DIDO 3; DIDO1; DIDO2; DIDO3; DIO 1; DIO1; hDido 1; hDido1; KIAA0333; DIDO1_HUMAN. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 細(xì)胞凋亡 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human, Mouse, (predicted: Rat, Chicken, Dog, Cow, Horse, Sheep, ) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:50-200 IHC-F=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 244kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DATF1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Apoptosis plays an important role in many cellular processes. In mice, the death inducer obliterator 1 (Dio1) gene, a putative transcription factor, is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. Dio1 expression is upregulated when an apoptosis is detected. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. Human DATF1 (death associated transcription factor 1) is similar to the mouse gene and therefore is thought to be involved in apoptosis. Function: Catalyzes the cleavage of the pyrrol ring of tryptophan and incorporates both atoms of a molecule of oxygen. Tissue Specificity: Ubiquitous. Similarity: Belongs to the indoleamine 2,3-dioxygenase family. Database links: Entrez Gene: 11083 Human Entrez Gene: 23856 Mouse Omim: 604140 Human SwissProt: Q9BTC0 Human SwissProt: Q8C9B9 Mouse Unigene: 15783 Human Unigene: 517172 Human Unigene: 253836 Mouse Unigene: 485484 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
