| 產(chǎn)品編號(hào) | bs-7640R-BF647 |
| 英文名稱(chēng)1 | Rabbit Anti-XKR1/BF647 Conjugated antibody |
| 中文名稱(chēng) | BF647標(biāo)記的膜轉(zhuǎn)運(yùn)蛋白XK抗體 |
| 別 名 | XK; Kell complex 37 kDa component; Membrane transport protein XK; XK related protein 1; XKR1; XRG1. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢(xún)價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 心血管 細(xì)胞生物 轉(zhuǎn)運(yùn)蛋白 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 49kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human XKR1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: XK is the Kell blood group 'precursor substance'. This protein has structural characteristics of prokaryotic and eukaryotic membrane transport proteins. The Kell blood group is constituted by two covalently linked antigens at the surface of red blood cells, Kell and KX. Whereas Kell is a metalloprotease with demonstrated in vitro enzymatic activity, the role of KX thereon, and/or alone, remains unknown, although its absence is linked to the McLeod syndrome, a neuroacanthocytosis. KX appears to be required for proper synthesis or presentation of the Kell antigens on the red blood cell surface. Function: May be involved in sodium-dependent transport of neutral amino acids or oligopeptides Subunit: Heterodimer with Kell; disulfide-linked. Subcellular Location: Membrane; Multi-pass membrane protein (Potential). Tissue Specificity: High levels in skeletal muscle, heart, brain, DISEASE: Defects in XK are the cause of McLeod syndrome (MLS) [MIM:300842]. It is an X-linked multisystem disorder characterized by late onset abnormalities in the neuromuscular and hematopoietic systems. Similarity: Belongs to the XK family. Database links: Entrez Gene: 7504 Human Entrez Gene: 22439 Mouse Omim: 314850 Human SwissProt: P51811 Human SwissProt: Q9QXY7 Mouse Unigene: 78919 Human Unigene: 56468 Mouse Unigene: 211877 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
