| 產(chǎn)品編號(hào) | bs-3839R-BF555 |
| 英文名稱1 | Rabbit Anti-eI4EBP2/BF555 Conjugated antibody |
| 中文名稱 | BF555標(biāo)記的eIF4E結(jié)合蛋白2抗體 |
| 別 名 | Regulates eIF4E activity by preventing its assembly into the eIF4F complex. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase pathway.Full=Eukaryotic translation initiation factor 4E-binding protein 2; 4E-BP2; eIF4E-binding protein 2; 4EBP2_HUMAN. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 染色質(zhì)和核信號(hào) 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞凋亡 轉(zhuǎn)錄調(diào)節(jié)因子 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Cow, ) |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 17/20kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human 4E-BP2 |
| 亞 型 | IgG |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | 0 |
| 產(chǎn)品介紹 |
background: This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection. [provided by RefSeq, Oct 2008] Function: Regulates eIF4E activity by preventing its assembly into the eIF4F complex. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase pathway. Subunit: Nonphosphorylated EIF4EBP2 interacts with EIF4E. Post-translational modifications: Phosphorylated on serine and threonine residues in response to insulin, EGF and PDGF. Similarity: Belongs to the eIF4E-binding protein family. Database links: Entrez Gene: 1979 Human Entrez Gene: 13688 Mouse Omim: 602224 Human SwissProt: Q13542 Human SwissProt: P70445 Mouse Unigene: 621200 Human Unigene: 730236 Human Unigene: 259516 Mouse Unigene: 24129 Rat |
