| 產(chǎn)品編號 | bs-9898R-BF488 |
| 英文名稱1 | Rabbit Anti-SISP1/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的應(yīng)激誘導(dǎo)分泌蛋白1抗體 |
| 別 名 | C10orf54; VISTA_HUMAN; Platelet receptor Gi24; stress induced secreted protein 1; UNQ730/PRO1412; V-type immunoglobulin domain-containing suppressor of T-cell activation; Stress-induced secreted protein-1; Sisp-1; V-set domain-containing immunoregulatory receptor; V-set immunoregulatory receptor; VSIR; B7-H5; B7H5; DD1alpha; GI24; PD-1H; PP2135; VISTA. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 心血管 細(xì)胞生物 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 31kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SISP1/GI24 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Platelet receptor GI24, also known as SISP1 or PP2135, is a 311 amino acid single-pass type I membrane protein that contains one Ig-like (immunoglobulin-like) domain. GI24 is thought to contribute to tumor-invasive growth in the collagen matrix and is encoded by a gene that maps to human chromosome 10q22.1. Chromosome 10 contains over 800 genes, 135 million nucleotides and comprises nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10. As with most trisomies, trisomy 10 is rare and is deleterious. Subcellular Location: Membrane. Similarity: Contains 1 Ig-like (immunoglobulin-like) domain. Database links: Entrez Gene: 64115 Human Entrez Gene: 74048 Mouse SwissProt: Q9H7M9 Human SwissProt: Q9D659 Mouse Unigene: 47382 Human Unigene: 273584 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
