產(chǎn)品編號 | IHC0642M |
英文名稱 | Mouse p53BP1 Ready-To-Use IHC Kit |
中文名稱 | 小鼠p53結(jié)合蛋白1即用型免疫組化試劑盒 |
別 名 | 53BP1; m53BP1; p202; p53BP1; TDRD30; TP53; TP53BP1; Trp53bp1 |
適用樣品基質(zhì) | FFPE tissue |
保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
產(chǎn)品介紹 |
53BP1 (P53-binding protein 1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, 53BP1 is phosphorylated and localizes to the presumptive sites of damage, specifically, double-strand breaks. 53BP1 may have a role in checkpoint signaling during mitosis, enhances TP53-mediated transcriptional activation, and participates in DNA repair by maintaining genomic stability. SWISS: Q12888 Gene ID: 7158 |
產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded Mouse brain tissue slide using IHC0642M (Mouse p53BP1 Kit).
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