| 產(chǎn)品編號 | IHC0631H |
| 英文名稱 | Human ADAM10 Ready-To-Use IHC Kit |
| 中文名稱 | 人去整合素樣金屬蛋白酶10（CD156c）即用型免疫組化試劑盒 |
| 別 名 | 1700031C13Rik; AD10; AD18; ADAM10; CD156c; CDw156; HsT18717; KUZ; kuzbanian; MADM; RAK; kuz |
| 適用樣品基質(zhì) | FFPE tissue |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
Proinflammatory cytokine tumor necrosis factor-a (TNF-a) contributes to a variety of inflammatory responses and programmed cell death. Notch receptor and its ligand participate in cell fate decisions during vertebrate development and are associated with several human disorders, including a T-cell lymphoma. TNF-a, notch and its ligand delta are all membrane-bond molecules, which are cleaved by proteases to release mature proteins or functional receptor. ADAM10, a metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease), was recently identified to cleave TNF-a, notch and its ligand delta (1-3). The genes encoding human, mouse, and bovine ADAM10 were recently cloned and designated ADAM 10, kuzbanian (KUZ), and MADM, respectively. ADAM10 mRNA is expressed in a variety of human and bovine tissues. |
| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded Human prostate cancer tissue slide using IHC0631H (Human ADAM10 Kit).
|
