| 產(chǎn)品編號 | IHC0614H |
| 英文名稱 | Human STING1 Ready-To-Use IHC Kit |
| 中文名稱 | 人跨膜蛋白173即用型免疫組化試劑盒 |
| 別 名 | SAVI; STING1; TMEM173; endoplasmic reticulum IFN stimulator; Endoplasmic reticulum interferon stimulator; ERIS; FLJ38577; hMITA; hSTING; Mediator of IRF3 activation; MITA; Mitochondrial mediator of IRF3 activation; MPYS; N terminal methionine proline tyrosine serine plasma membrane tetraspanner; NET23; Stimulator of interferon genes; Stimulator of interferon genes protein; STING; TM173_HUMAN; Tmem173; Transmembrane protein 173 |
| 適用樣品基質(zhì) | FFPE tissue |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
STING is a 379 amino acid containing signaling protein that acts as an important component of innate immune signaling. This signaling protein is able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression. STING may have translocon function, the translocon possibly being able to influence the induction of type I interferons and is also involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II) thus facilitating the detection of intracellular viral RNA species as well as B-form DNA and mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway. Generally seen in endoplasmic reticulum membrane, cell membrane and mitochondrion outer membrane, it is ubiquitously expressed in most of tissues. |
| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded Human prostate cancer tissue slide using IHC0614H (Human STING1 Kit).
Immunohistochemical analysis of paraffin embedded Human ovarian cancer tissue slide using IHC0614H (Human STING1 Kit).
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Immunohistochemical analysis of paraffin embedded Human colon cancer tissue slide using IHC0614H (Human STING1 Kit).
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Immunohistochemical analysis of paraffin embedded Human colon tissue slide using IHC0614H (Human STING1 Kit).
Immunohistochemical analysis of paraffin embedded Human tonsil tissue slide using IHC0614H (Human STING1 Kit).
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