產(chǎn)品編號(hào) | IHC0611H |
英文名稱 | Human CD133 Ready-To-Use IHC Kit |
中文名稱 | 人造血干細(xì)胞抗原CD133即用型免疫組化試劑盒 |
別 名 | AC133; CD133; CORD12; MCDR2; MSTP061; PROM1; PROML1; RP41; STGD4 |
適用樣品基質(zhì) | FFPE tissue |
保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
產(chǎn)品介紹 |
The CD133 (AC133) antigen is a 97 kDa glycoprotein, with 5 transmembrane domains, that shows up as a 120 kDa band on protein gels due to glycosylation. CD133 is a cell surface marker expressed by immature hematopoietic stem cells but not mature blood cells. In addition to hematopoietic stem and progenitor cells, CD133 has been found to be a marker for other stem and progenitor cells including neural and embryonic stem cells. CD133 has been shown to be expressed in cancers, including some leukemias and brain tumors, that may be derived from stem cells. Low level expression could also be detected in the kidney, pancreas, placenta, and fetal liver. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of the CD133 gene is also associated with several types of cancer. CD133 is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner, and multiple transcript variants encoding different isoforms have been found. SWISS: O43490 Gene ID: 8842 |
產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded Human pancreas tissue slide using IHC0611H (Human CD133 Kit).
Immunohistochemical analysis of paraffin embedded Human kidney tissue slide using IHC0611H (Human CD133 Kit).
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