產(chǎn)品編號(hào) | IHC0586R |
英文名稱 | Rat CD15/SSEA1 Ready-To-Use IHC Kit |
中文名稱 | 大鼠CD15/SSEA1即用型免疫組化試劑盒 |
別 名 | LeX; CD15; ELFT; FCT3A; FUTIV; SSEA-1; FUC-TIV; FCT3A; Fucosyltransferase 4; Fucosyltransferase IV; FUT4; SSEA 1 |
適用樣品基質(zhì) | FFPE tissue |
保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
產(chǎn)品介紹 |
CD15 (Lewis X, Le(x); stage specific embryonic antigen-1, SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin's disease. SWISS: P22083 Gene ID: 2526 |
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