產(chǎn)品編號 | IHC0582M |
英文名稱 | Mouse PAX5 Ready-To-Use IHC Kit |
中文名稱 | 小鼠配對盒基因5即用型免疫組化試劑盒 |
別 名 | ALL3; BSAP; EBB-1; KLP; Pax-5; PAX5; B-cell-specific transcription factor |
適用樣品基質(zhì) | FFPE tissue |
保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
產(chǎn)品介紹 |
PAX5 is a member of the paired box (PAX) family of transcription factors. The PAX proteins are important regulators in early development and alterations in the expression of their genes are thought to contribute to neoplastic transformation. PAX5 is the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages, of B-cell differentiation. Its expression has also been detected in developing CNS and testis, therefore, PAX5 may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis. Mutations in the gene can result in leukemia, acute lymphoblastic 3. SWISS: Q02548 Gene ID: 5079 |
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