產(chǎn)品編號 | IHC0580R |
英文名稱 | Rat LRP/MVP Ready-To-Use IHC Kit |
中文名稱 | 大鼠肺耐藥相關(guān)蛋白即用型免疫組化試劑盒 |
別 名 | LRP; MVP; VAULT1; 2310009M24Rik; Lung Resistance Related Protein |
適用樣品基質(zhì) | FFPE tissue |
保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
產(chǎn)品介紹 |
This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts. SWISS: Q14764 Gene ID: 9961 |
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