產(chǎn)品編號(hào) | IHC0553H |
英文名稱 | Human Ig kappa light chain Ready-To-Use IHC Kit |
中文名稱 | 人k輕鏈即用型免疫組化試劑盒 |
別 名 | HCAK 1; HCAK1; IGKC; MGC11157; IGKCD; Km; Human Kappa Light Chain |
適用樣品基質(zhì) | FFPE tissue |
保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
產(chǎn)品介紹 |
Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five types) and two light chains (kappa, lambda; both having a molecular weight of 22.5 kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30. Antibodies to the kappa light chain are reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant. SWISS: P01834 Gene ID: 3514 |
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