產(chǎn)品編號(hào) | IHC0551H |
英文名稱 | Human GRP94 Ready-To-Use IHC Kit |
中文名稱 | 人葡萄糖調(diào)節(jié)蛋白94即用型免疫組化試劑盒 |
別 名 | ECGP; endoplasmin; ERp99; GP96; GRP94; HEL-S-125m; HEL35; HSP90B1; HSPC4; TA-3; Targ2; Tra-1; TRA1 |
適用樣品基質(zhì) | FFPE tissue |
保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
產(chǎn)品介紹 |
GRP94 is a 803 amino acid protein belonging to the heat shock protein 90 family. It acts as a molecular chaperone that functions in the processing and transport of secreted proteins. GRP94 and its N-terminal fragment stimulates CTL expansion and maturation of human monocyte-derived dendritic cells (MDDC). It plays a central role in innate as well as acquired immunity, maturation and chemotaxis of dendritic cells, Ab production, cross-priming, as a potential marker in breast cancer and is a peptide acceptor in endoplasmic reticulum and an accessory to peptide loading of MHC class I molecules. Expression of GRP94 suppressed A23187-induced apoptosis and stabilized calcium homeostasis. GRP94 is expressed in melanoma or liver metastases of colon carcinoma cells, human gastric carcinoma BGC-823 cells. SWISS: P14625 Gene ID: 7184 |
產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded Human prostate cancer tissue slide using IHC0551H (Human GRP94 Kit).
Immunohistochemical analysis of paraffin embedded Human brain tissue slide using IHC0551H (Human GRP94 Kit).
Immunohistochemical analysis of paraffin embedded Human colon cancer tissue slide using IHC0551H (Human GRP94 Kit).
Immunohistochemical analysis of paraffin embedded Human colon tissue slide using IHC0551H (Human GRP94 Kit).
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