產(chǎn)品編號(hào) | IHC0501H |
英文名稱(chēng) | Human CD7 Ready-To-Use IHC Kit |
中文名稱(chēng) | 人CD7即用型免疫組化試劑盒 |
別 名 | LEU-9; CD7; CD7 antigen (p41); CD7 molecule; CD7_HUMAN; T-cell antigen CD7; T-cell leukemia antigen; T-cell surface antigen Leu-9; CD 7; CD7 antigen; CD7 antigen p41; CD7 molecule; GP 40; GP40; LEU 9; LEU9; p41; p41 protein; T cell antigen CD7; T cell ant |
適用樣品基質(zhì) | FFPE tissue |
保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
產(chǎn)品介紹 |
CD7 (gp40, Leu9) is a 40 kDa member of the immunoglobulin gene superfamily. CD7 contains N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxy-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. Further, CD7 is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation. Expression of CD7 is an important marker used in leukemia diagnostics. SWISS: P09564 Gene ID: 924 |
產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded human spleen tissue slide using IHC0501H (Human CD7 IHC Kit).
Immunohistochemical analysis of paraffin embedded human colon cancer tissue slide using IHC0501H (Human CD7 IHC Kit).
Immunohistochemical analysis of paraffin embedded human lung cancer tissue slide using IHC0501H (Human CD7 IHC Kit).
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