| 產(chǎn)品編號 |
IHC0359M |
| 英文名稱 |
Mouse SOX9 Ready-To-Use IHC Kit
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| 中文名稱 |
小鼠轉(zhuǎn)錄因子SOX9蛋白即用型免疫組化試劑盒 |
| 別 名 |
2010306G03Rik, AV220920, CMD1, CMPD1, mKIAA4243, Sox-9, SOX9, SRA1, SRXX2, SRXY10 |
| 保存條件 |
Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
SOX9 has a role in sex determination and differentiation of Sertoli cells. It is involved in chondrogenesis and regulates the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes. Translocation of this gene can cause campomelic dysplasia. SOX9 is involved in the formation of testes from the indifferent fetal gonads. It is a major molecular component of the neuron-glia switch in developing spinal cord. During normal development, SOX9 allows the prostate epithelium to outgrow into the mesenchyme and then provides basal cell support for development and maintenance of the luminal epithelium. These functions of SOX9 are subverted in prostate cancer to support tumor growth and invasion. SOX9 may direct the formation of neural crest precursors and the development of a range of neural crest derivative. It has a transcriptional regulation in melanin production in cells. Northern blot analysis shows its expression on adult testis, adult heart, and fetal brain.
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| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded mouse colon tissue slide using IHC0359M (Mouse SOX9 Kit).
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