| 產(chǎn)品編號(hào) | IHC0322H |
| 英文名稱 | Human E-Selectin Ready-To-Use IHC Kit |
| 中文名稱 | 人E選擇素即用型免疫組化試劑盒 |
| 別 名 | ELAM, ELAM1, LECAM2, CD62E, SELE, ESEL, E-Selectin |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
Leukocytes adhere to the blood vessel endothelium during extravasation in postcapillary venules of lymph nodes. In addition, leukocyte adhesion occurs in the capillaries and small venules at any site in the body after onset of inflammation. This response is immediate and involves a cascade of adhesion receptors. At the endothelial surface members of the selectin and immunoglobulin superfamilies participate in this cascade. Selectins are C-type cell surface lectins that play a role in leukocyte adhesion to the blood vessel wall endothelium. E-selectin (CD62E) is an endothelial cell specific selectin that is expressed only after activation with proinflammatory cytokines. In vitro experiments have shown that IL-1, TNFalpha and bacterial wall components like lipopolysaccharides induce the transcription of E-selectin in a NFkB dependent signaling cascade. E-selectin has been associated with blood vessel endothelium in diverse inflammatory situations. |
| 產(chǎn)品圖片 |
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Immunohistochemical analysis of paraffin embedded human colon cancer tissue slide using IHC0322H (Human E-Selectin Kit).
Immunohistochemical analysis of paraffin embedded human tonsil tissue slide using IHC0322H (Human E-Selectin Kit).
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