| 產(chǎn)品編號 | IHC0316H |
| 英文名稱 | Human ICAM1 Ready-To-Use IHC Kit |
| 中文名稱 | 人細(xì)胞間粘附分子-1即用型免疫組化試劑盒 |
| 別 名 | ICAM, Icam-1, Ly-47, MALA-2, BB2, CD54 antigen, CD54, ICAM1, ICAM 1, ICAM-1, Cell surface glycoprotein P3.58, Human rhinovirus receptor, Intercellular adhesion molecule 1, Major group rhinovirus receptor, MALA2, MyD10, P3.58, Surface antigen of activated |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
ICAM-1 (CD54) is an 85-110 kDa single-chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. ICAM-1 has 7 potential N-linked glycosylation sites and shares considerable amino acid sequence homology with ICAM-3 (CD50) and ICAM-2 (CD102). ICAM-1 binds to integrins of type CD11a/CD18 (leukocyte adhesion molecule, LFA-1), or CD11b/CD18 (Mac-1) and is exploited by Rhinovirus as a receptor. ICAM-1 is expressed by activated endothelial cells and detected on epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase upon inflammation. ICAM-1 is also detected in some carcinoma and melanoma cells. Soluble ICAM-1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes. |
| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded human spleen tissue slide using IHC0316H (Human ICAM1 Kit).
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Immunohistochemical analysis of paraffin embedded human colon cancer tissue slide using IHC0316H (Human ICAM1 Kit).
Immunohistochemical analysis of paraffin embedded human lung cancer tissue slide using IHC0316H (Human ICAM1 Kit).
Immunohistochemical analysis of paraffin embedded human tonsil tissue slide using IHC0316H (Human ICAM1 Kit).
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