| 產(chǎn)品編號 | IHC0315R |
| 英文名稱 | Rat N Cadherin Ready-To-Use IHC Kit |
| 中文名稱 | 大鼠N-鈣粘附分子即用型免疫組化試劑盒 |
| 別 名 | cadherin-2, N-cadherin, CDH4, CAD4, R-CAD, RCAD, CDH3, CDHP, HJMD, PCAD, CD325, CDHN, CDw325, NCAD, N Cadherin, CDH2, Arc-1, CD324, CDHE, ECAD, LCAM, UVO |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
N-cadherin is a 140 kDa protein belonging to a family of transmembrane molecules that mediate calcium-dependent intercellular adhesion. Cadherins are involved in controlling morphogenetic movements during development and regulate cell surface adhesion through homotypic adhesion with the same cadherin species. N-cadherin's function is dependent on its association with the actin-cytoskeleton and is mediated through interactions between the C-terminal region of N-cadherin and the cytoplasmic catenin proteins. The stability of this association is regulated by phosphorylation and dephosphorylation of beta-catenin. Further, N-cadherin is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. |
| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded rat heart tissue slide using IHC0315R (Rat N Cadherin Kit).
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