| 產(chǎn)品編號(hào) | IHC0315 |
| 英文名稱 | N Cadherin Ready-To-Use IHC Kit |
| 中文名稱 | N-鈣粘附分子即用型免疫組化試劑盒 |
| 別 名 | cadherin-2, N-cadherin, CDH4, CAD4, R-CAD, RCAD, CDH3, CDHP, HJMD, PCAD, CD325, CDHN, CDw325, NCAD, N Cadherin, CDH2, Arc-1, CD324, CDHE, ECAD, LCAM, UVO |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
N-cadherin is a 140 kDa protein belonging to a family of transmembrane molecules that mediate calcium-dependent intercellular adhesion. Cadherins are involved in controlling morphogenetic movements during development and regulate cell surface adhesion through homotypic adhesion with the same cadherin species. N-cadherin's function is dependent on its association with the actin-cytoskeleton and is mediated through interactions between the C-terminal region of N-cadherin and the cytoplasmic catenin proteins. The stability of this association is regulated by phosphorylation and dephosphorylation of beta-catenin. Further, N-cadherin is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. |
| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded mouse heart tissue slide using IHC0315 (N Cadherin Kit).
Immunohistochemical analysis of paraffin embedded human heart tissue slide using IHC0315 (N Cadherin Kit).
Immunohistochemical analysis of paraffin embedded rat heart tissue slide using IHC0315 (N Cadherin Kit).
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