產(chǎn)品編號(hào) | IHC0312H |
英文名稱 | Human AFP Ready-To-Use IHC Kit |
中文名稱 | 人甲胎蛋白即用型免疫組化試劑盒 |
別 名 | AFP, AFPD, FETA, HPAFP, alpha 1 Fetoprotein |
保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
產(chǎn)品介紹 |
AFP (Alpha Fetoprotein) is a major plasma protein produced by the yolk sac, intestinal tract and the liver during fetal life. AFP expression in adults is often associated with hepatoma or teratoma. However, hereditary persistence of AFP may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. AFP is found in monomeric, dimeric, and trimeric forms. AFP can also bind to copper ions, nickel ions, fatty acids and bilirubin. The level of AFP in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. High level of serum AFP has been identified in patients with hepatocellular carcinomas (HCC), teratoblastoma, colorectal cancer, pancreatic cancer, and germ cell neoplasms. |
產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded human hepatocellular carcinoma tissue slide using IHC0312H (Human AFP Kit).
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