| 產(chǎn)品編號(hào) | D60222 |
| 英文名稱 | 17-AAG |
| 中文名稱 | 坦螺旋霉素 |
| 別 名 | CP 127374; NSC 330507; KOS 953 |
| 克 隆 號(hào) | |
| CAS | 75747-14-7 |
| 理論分子量 | 585.69 kDa |
| 檢測分子量 | |
| 保存條件 | -20℃ |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
Tanespimycin (17-AAG) is a potent HSP90 inhibitor with an IC50 of 5 nM, having a 100-fold higher binding affinity for tumour cell derived HSP90 than normal cell derived HSP90. Tanespimycin depletes cellular STK38/NDR1 and reduces STK38 kinase activity. Tanespimycin also downregulates the stk38 gene expression |
