| 產(chǎn)品編號 | D51679 |
| 英文名稱 | Gefitinib-based PROTAC 3 |
| 中文名稱 | |
| CAS | 2230821-27-7 |
| 理論分子量 | 934.51kDa |
| 性 狀 | Lyophilized |
| 保存條件 | Store in dry, dark place for one year. |
| 產(chǎn)品介紹 |
NTN21277, also known as Gefitinib-based PROTAC 3 is a VHL-recruiting PROTAC that induces the degradation of EGFR and EGFR mutants with DC50 of 11.7 nM and 22.3 nM for HCC827 cell (Exon 19 del) and H3255 cell (L858R). |
