| 產(chǎn)品編號(hào) | D51663 |
| 英文名稱 | SR-59230A oxalate |
| 中文名稱 | |
| 別 名 | β3-adrenergic receptor拮抗劑 |
| CAS | 174689-39-5 |
| 理論分子量 | 415.48kDa |
| 性 狀 | Lyophilized |
| 保存條件 | Store in dry, dark place for one year. |
| 產(chǎn)品介紹 |
SR-59230A is a potent and selective β3 adrenoceptor antagonist (IC50 values are 40, 408 and 648 nM for β3, β1 and β2 receptors respectively). SR-59230A was subsequently shown to also act at α1 adrenoceptors at high doses. It has been shown to block the hyperthermia produced by MDMA in animal studies. SR 59230A blocks MDMA-induced hyperthermia, while at high concentrations it blocks hyperthermia but also increases heat loss through an α1-AR antagonistic mechanism. |
