| 產(chǎn)品編號(hào) | D51662 |
| 英文名稱 | ML277 |
| 中文名稱 | |
| 別 名 | KCNQ1通道激活劑 |
| CAS | 1401242-74-7 |
| 理論分子量 | 471.59kDa |
| 性 狀 | Lyophilized |
| 保存條件 | Store in dry, dark place for one year. |
| 產(chǎn)品介紹 |
ML277 is a potent activator of KCNQ1 (Kv7.1) channels with >100-fold selectivity versus KCNQ2 and KCNQ4 and no activity against the hERG potassium channel up to 30 μM. KCNQ1 is a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. ML277 is the first selective and potent activator found, with an EC50 of 260 nM. |
