產(chǎn)品編號 | bsm-51336M |
英文名稱 | RPA2 Mouse mAb |
中文名稱 | 復(fù)制因子A蛋白2單克隆抗體 |
別 名 | RFA2_HUMAN; Replication protein A 32 kDa subunit; RP-A p32; Replication factor A protein 2(RF-A protein 2); Replication protein A 34 kDa subunit(RP-A p34); REPA2; RPA32; RPA34; replication protein A2; RP-A p34; |
抗體來源 | Mouse |
克隆類型 | Monoclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat) |
產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 29 kDa |
檢測分子量 | |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | Recombinant human RPA2 Protein |
亞 型 | IgG1,Κ |
純化方法 | affinity purified by Protein A |
緩 沖 液 | PBS with 0.02% Proclin300. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions.
Functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair; it does not support chromosomal DNA replication and cell cycle progression through S-phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange. SWISS: P15927 Gene ID: 6118 |