| 產(chǎn)品編號(hào) | bsm-60310M |
| 英文名稱 | Mouse Anti-CCDC101 antibody |
| 中文名稱 | |
| 抗體來(lái)源 | Mouse |
| 克隆類型 | Monoclonal |
| 克 隆 號(hào) | B8C5 |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat) |
| 產(chǎn)品應(yīng)用 | WB=1:1000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 亞 型 | IgG1/Kappa |
| 純化方法 | affinity purified by Protein G |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | 一些組蛋白乙酰轉(zhuǎn)移酶（HAT）SAGA型復(fù)合物的染色質(zhì)讀取器成分，如TFTC-HAT、ATAC或STAGA復(fù)合物。SGF29特異性識(shí)別和結(jié)合組蛋白H3（H3K4me）的甲基化‘Lys-4’，偏好三甲基化形式（H3K4me3）。在SAGA型配合物中，SGF29需要向H3K4me招募配合物。通過(guò)向H3K4me招募SAGA復(fù)合物參與內(nèi)質(zhì)網(wǎng)（ER）應(yīng)激反應(yīng)，從而促進(jìn)組蛋白H3乙酰化和細(xì)胞存活。 |
