| 產(chǎn)品編號 | bs-43043P |
| 英文名稱 | Recombinant human IL-7R Alpha / CD127 protein, His (HEK293) |
| 中文名稱 | 重組人白細胞介素-7受體a（CD127）蛋白 |
| 別 名 | Interleukin-7 receptor subunit alpha; IL7R; CD 127; CD127; CD127 antigen; CDW127; IL 7R alpha; IL 7R; IL-7 receptor subunit alpha; IL-7R subunit alpha; IL-7R-alpha; IL-7RA; IL7RA; IL7Ralpha; ILRA; Interleukin 7 receptor alpha chain; Interleukin 7 receptor |
| 理論分子量 | 29.3 kDa |
| 檢測分子量 | 40-70 |
| 性 狀 | Liquid |
| 濃 度 | ＞0.5 mg/ml |
| 物 種 | Human |
| 序 列 | 21-239/459 |
| 純 度 | >95% as determined by SDS-PAGE |
| 純化方法 | AC |
| 內(nèi)毒素 | Not analyzed |
| 表達系統(tǒng) | HEK293 cell |
| 活性 | Yes |
| 標(biāo)簽 | His |
| 緩 沖 液 | PBS (pH7.4). |
| 保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). |
| 產(chǎn)品圖片 |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
|
