產(chǎn)品編號 | D50449 |
英文名稱 | 2,3-DCPE hydrochloride |
中文名稱 | 2,3-DCPE鹽酸鹽 |
別 名 | 2,3-DCPE; |
克 隆 號 | |
CAS | 418788-90-6 |
理論分子量 | kDa |
檢測分子量 | |
保存條件 | Store at -20℃. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
CAS號:418788-90-6 分子式:C11H15Cl2NO2.HCl 分子量:300.61 純度:99%(HPLC) 熔點:139-142℃ 沸點:429.8℃ at 760 mmHg 溶解性:Soluble in water (>25 mg/ml), ethanol (~20 mg/ml), DMSO (~20 mg/ml), DMF (~20 mg/ml), and PBS (pH7.2) (~10 mg/ml). 產(chǎn)品描述:2,3 DCPE displays anticancer agent properties and induces ERK activation. Causes apoptosis in many tumor cell lines and is known to specifically cleave caspase-8, caspase-3, caspase-9, and poly(ADP-ribose) polymerase in cancer cells, but not in human fibroblasts. Shown to reduce the protein level of Bcl-XL. Triggered cell death in OAW42-R ovarian carcinoma cells with inhibition of Bcl-2 expression and increased cytotoxic effect of cisplatin in OAW42-R resistant cells. 2,3-DCPE reported to induce S-phase arrest and upregulate p21. IC50:LoVo colon cancer cell line: IC50 = 0.89 μM (human); normal fibroblasts: IC50 = 12.6 μM (human) 用途:A compound that induces both upregulation and S-phase arrest in p21. |
1、抗體溶解方法 | |
2、抗體修復(fù)方式 | |
3、常用試劑的配制 | |
4、免疫組化操作步驟 | |
5、免疫組化問題解答 | |
6、Western Blotting 操作步驟 | |
7、Western Blotting 問題解答 | |
8、關(guān)于肽鏈的設(shè)計 | |
9、多肽的溶解與保存 | |
10、酶標抗體效價測定程序 | |