| 產(chǎn)品編號(hào) | bs-19779R |
| 英文名稱 | Rabbit Anti-RBMXL2 antibody |
| 中文名稱 | RBMXL2蛋白抗體 |
| 別 名 | Heterogeneous nuclear ribonucleoprotein G T; hnRNP G T; hnRNP G-T; HNRNPG T; HNRNPGT; HNRPGT; RBMX L2; RBMXL 2; RBMXL2; RMXL2_HUMAN; RNA binding motif protein X linked like 2; RNA-binding motif protein; Testes specific heterogenous nuclear ribonucleoprotein G T; Testis-specific heterogeneous nuclear ribonucleoprotein G-T; X-linked-like-2. |
| 研究領(lǐng)域 | 細(xì)胞生物 發(fā)育生物學(xué) 結(jié)合蛋白 表觀遺傳學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 43kDa |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RBMXL2: 221-320/392 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene belongs to the HNRPG subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind RNAs. This gene is intronless and is thought to be derived from a processed retroposon. However, unlike many retroposon-derived genes, this gene is not a pseudogene. The encoded protein has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility. [provided by RefSeq, Jul 2008] Subcellular Location: Nucleus. Tissue Specificity: Expressed predominantly in spermatocytes and less in round spermatids (at protein level). Expressed in germ cells. Similarity: Contains 1 RRM (RNA recognition motif) domain. SWISS: O75526 Gene ID: 27288 Database links: Entrez Gene: 27288 Human Entrez Gene: 76572 Mouse Omim: 605444 Human SwissProt: O75526 Human Unigene: 121605 Human |
