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MATH5 Rabbit pAb (bs-18692R)  
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50ul/1180.00元
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產(chǎn)品編號(hào) bs-18692R
英文名稱 MATH5 Rabbit pAb
中文名稱 MATH5蛋白抗體
別    名 ATOH7; ATOH7_HUMAN; Atonal homolog 7(Drosophila); Atonal Homolog 7; bHLHa13; Class A basic helix-loop-helix protein 13; hATH5; Helix-loop-helix protein hATH-5; Math5; Protein atonal homolog 7.  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  新陳代謝  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse (predicted: Human,Rat,Rabbit,Sheep,Cow,Chicken,Dog,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 17 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MAT2A: 31-120/152 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This intronless gene encodes a member of the basic helix-loop-helix family of transcription factors, with similarity to Drosophila atonal gene that controls photoreceptor development. Studies in mice suggest that this gene plays a central role in retinal ganglion cell and optic nerve formation. Mutations in this gene are associated with nonsyndromic congenital retinal nonattachment. [provided by RefSeq, Dec 2011]

Function:
Transcription factor involved in the differentiation of retinal ganglion cells.

Subunit:


Subcellular Location:
Nucleus.

Post-translational modifications:
The alpha' subunit is a post-translationally modified version of MAT2A.

Similarity:
Contains 1 basic helix-loop-helix (bHLH) domain.

SWISS:
Q8N100

Gene ID:
220202

Database links:

Entrez Gene: 220202 Human

Entrez Gene: 53404 Mouse

Entrez Gene: 365564 Rat

Omim: 609875 Human

SwissProt: Q8N100 Human

SwissProt: Q9Z2E5 Mouse

Unigene: 175396 Human

Unigene: 228661 Mouse



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (mouse intestine); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (MATH5) Polyclonal Antibody, Unconjugated (bs-18692R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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