| 產(chǎn)品編號 | bs-17099R |
| 英文名稱 | Lano/LRRC1 Rabbit pAb |
| 中文名稱 | 富含亮氨酸重復序列蛋白1抗體 |
| 別 名 | dJ523E19.1; FLJ10775; FLJ11834; LANO adapter protein; LAP and no PDZ protein; Leucine rich repeat containing protein 1; Leucine-rich repeat-containing protein 1; Lrrc1; LRRC1_HUMAN. |
| 研究領域 | 腫瘤 細胞生物 免疫學 發(fā)育生物學 轉錄調節(jié)因子 表觀遺傳學 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應 | (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Dog,Horse) |
| 產(chǎn)品應用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 59 kDa |
| 檢測分子量 | |
| 細胞定位 | 細胞漿 細胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Lano/LRRC1: 261-360/524 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The primary function of these motifs is to provide a versatile structural framework to mediate the formation of protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. LRRC1 (leucine-rich repeat-containing protein 1), also known as LANO adapter protein or LAP and no PDZ protein, is a 524 amino acid protein that contains 17 LRR repeats. Localized to the cytoplasm and the membrane, LRRC1 is expressed strongly in placenta and testis, with lower levels found in heart, kidney, thyroid, lung, prostate, colon and trachea. LRRC1 interacts with PSD-95 and SAP 97, and may form a complex with SAP 97 and ERBIN. LRRC1 is expressed as two isoforms produced by alternative splicing events. Subunit: Interacts with DLG1 and DLG4. May form a complex with DLG1 and ERBB2IP, where interaction between LRRC1 and ERBB2IP is indirect. Subcellular Location: Cytoplasm. Membrane. Localized at the basolateral side of epithelial cells. Tissue Specificity: Expressed strongly in testis and placenta, followed by heart, lung, kidney, thyroid, trachea, colon, prostate and pancreas. Similarity: Contains 17 LRR (leucine-rich) repeats. SWISS: Q9BTT6 Gene ID: 55227 Database links: Entrez Gene: 55227 Human Omim: 608195 Human SwissProt: Q9BTT6 Human Unigene: 646997 Human Unigene: 657695 Human |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
