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QRFP Rabbit pAb (bs-11534R)  
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50ul/1180.00元
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產(chǎn)品編號 bs-11534R
英文名稱 QRFP Rabbit pAb
中文名稱 神經(jīng)內(nèi)分泌肽QRFP抗體
別    名 26RFa; Neuropeptide RF-amide; OX26_HUMAN; pyroglutamylated RFamide peptide; P518; Pyroglutamylated arginine-phenylalanine-amide peptide; QRF-amide; Qrfp.  
研究領域 心血管  細胞生物  神經(jīng)生物學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,Rat (predicted: Human,Pig,Sheep,Cow,Horse)
產(chǎn)品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 5 kDa
檢測分子量
細胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human QRFP: 91-133/136 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 QRFP is a 136 amino acid secreted protein that is widely expressed in the brain with highest expression levels in the cerebellum, medulla, pituitary, retina, vestibular nucleus and white matter. Also expressed in the bladder, colon, coronary artery, parathyroid gland, prostate, testis and thyroid, QRFP is a member of the RFamide neuropeptide family. QRFP may be involved in aldosterone secretion by the adrenal gland and is also implicated in stimulating metabolic rate, locomotor activity and increasing blood pressure. Considered a ligand for the G-protein coupled receptor GPR103, QRFP may have orexigenic activity, thereby acting as an appetite stimulant. The gene encoding QFRP is located on human chromosome 9, which consists of about 145 million bases, comprises roughly 4% of the human genome and encodes nearly 900 genes.

Function:
Stimulates feeding behavior, metabolic rate and locomotor activity and increases blood pressure. May have orexigenic activity. May promote aldosterone secretion by the adrenal gland.

Subunit:
Ligand for the G-protein coupled receptor QRFPR/GPR103

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed widely in the brain with highest expression levels in the cerebellum, medulla, pituitary, retina, vestibular nucleus, and white matter. Also expressed in the bladder, colon, coronary artery, parathyroid gland, prostate, testis, and thyroid.

Similarity:
Belongs to the RFamide neuropeptide family.

SWISS:
P83859

Gene ID:
347148

Database links:

Entrez Gene: 347148 Human

Omim: 609795 Human

SwissProt: P83859 Human

Unigene: 660704 Human



產(chǎn)品圖片
Sample: Lane 1: Mouse Cerebrum tissue lysates Lane 2: Rat Cerebrum tissue lysates Primary: Anti-QRFP (bs-11534R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 5 kDa Observed band size: 18 kDa
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