| 產(chǎn)品編號(hào) | bsm-61521R |
| 英文名稱 | Fibulin 5 Recombinant Rabbit mAb |
| 中文名稱 | 衰老關(guān)鍵蛋白重組兔單抗 |
| 別 名 | Fibulin-5; FIBL-5; Fibulin 5; FIBL 5; Fibulin5; FIBL5; Dance; Urine p50 protein; UP50; DANCE. |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號(hào) | |
| 交叉反應(yīng) | Human,Mouse |
| 產(chǎn)品應(yīng)用 | WB=1:1000-1:2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 50 kDa |
| 檢測(cè)分子量 | 50 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human Fibulin 5: 250-448/448 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN.Stabilizes and organizes elastic fibers in the skin, lung and vasculature.Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling. SWISS: Q9UBX5 Gene ID: 10516 Fibulin-5 Fibulin-5亦稱為FBLN-5、DANCE或EVEC是細(xì)胞外基質(zhì)蛋白質(zhì)家族的一員，在組織器官發(fā)育、重塑和修復(fù)過(guò)程中起重要作用，并與內(nèi)皮細(xì)胞相互作用.Fibulin-5廣泛分布于富含彈性蛋白的組織, 能直接與原彈性蛋白結(jié)合,并將后者錨于細(xì)胞表面,這對(duì)形成彈性纖維十分關(guān)鍵, 對(duì)血管的發(fā)育和修復(fù)具有重要作用.此外,Fibuljn-5還能促進(jìn)創(chuàng)口愈合, 與細(xì)胞的增殖、運(yùn)動(dòng)和侵襲有關(guān) fibulin-5有學(xué)者稱“皮膚衰老關(guān)鍵蛋白”與皮膚彈性有關(guān)的蛋白，對(duì)于起著固定細(xì)胞外壁、保持肌膚緊繃、 |
| 產(chǎn)品圖片 |
Western blot analysis of mouse heart lysate. Using Fibulin 5 (bsm-61521R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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