截止目前，引用Bioss產品發(fā)表的文獻共19603篇，總影響因子87327.086分，發(fā)表在Nature, Science, Cell以及Immunity等頂級期刊的文獻共53篇，合作單位覆蓋了清華、北大、復旦、華盛頓大學、麻省理工學院、東京大學以及紐約大學等國際知名研究機構上百所。
我們每月收集引用Bioss產品發(fā)表的文獻。若您在當月已發(fā)表SCI文章，但未被我公司收集，請致電Bioss，我們將贈予現(xiàn)金鼓勵，金額標準請參考“發(fā)文章 領獎金”活動頁面。
近期收錄2022年7月引用Bioss產品發(fā)表的文獻共247篇（圖一，綠色柱），文章影響因子(IF) 總和高達1703.345，其中，20分以上文章3篇，10分以上文獻39篇（圖二）。
圖一
圖二
Molecular Cancer [IF=41.444]
Anti-ATPase Na+/ K+ beta 2(Loading Control) pAb; WB
作者單位：美國紐約西奈山伊坎醫(yī)學院醫(yī)學系
摘要：Background
Long Interspersed Nuclear Element-1 (LINE-1, L1) is increasingly regarded as a genetic risk for lung cancer. Transcriptionally active LINE-1 forms a L1-gene chimeric transcript (LCTs), through somatic L1 retrotransposition (LRT) or L1 antisense promoter (L1-ASP) activation, to play an oncogenic role in cancer progression.
Methods
Here, we developed Retrotransposon-gene fusion estimation program (ReFuse), to identify and quantify LCTs in RNA sequencing data from TCGA lung cancer cohort (n?=?1146) and a single cell RNA sequencing dataset then...
Signal Transduction and Targeted
Therapy [IF=38.104]
作者單位：中山大學生命科學學院
摘要：SARS-CoV-2, the culprit pathogen of COVID-19, elicits prominent immune responses and cytokine storms. Intracellular Cl? is a crucial regulator of host defense, whereas the role of Cl? signaling pathway in modulating pulmonary inflammation associated with SARS-CoV-2 infection remains unclear. By using human respiratory epithelial cell lines, primary cultured human airway epithelial cells, and murine models of viral structural protein stimulation and SARS-CoV-2 direct challenge, we demonstrated that SARS-CoV-2 nucleocapsid (N) protein could interact with Smad3, which downregulated cystic fibrosis transmembrane conductance regulator (CFTR) expression via microRNA-145. The intracellular Cl? concentration ([Cl?]i) was raised, resulting in phosphorylation of serum glucocorticoid regulated kinase 1 (SGK1) and robust inflammatory responses. Inhibition or knockout of SGK1 abrogated the N protein-elicited airway inflammation. Moreover, N protein promoted a sustained elevation of [Cl?]i by depleting intracellular cAMP via upregulation of phosphodiesterase 4 (PDE4). Rolipram, a selective PDE4 inhibitor, countered airway inflammation by reducing [Cl?]i. Our findings suggested that Cl? acted as the crucial pathological second messenger mediating the inflammatory responses after SARS-CoV-2 infection. Targeting the Cl? signaling pathway might be a novel therapeutic strategy for COVID-19.
Cell Stem Cell [IF=25.269]
文獻引用抗體：
bs-3155R;Anti-Phospho-GCN2 (Thr899) pAb
bs-2469R;Anti-PERK pAb
Nature Communications
[IF=17.694]
文獻引用抗體：
bs-12702R-HRP;Anti-phospho-DRP1 (Ser616)/HRP pAb; IHC,IF
bs-0080R;Anti-CD20 pAb; IHC,IF
作者單位：中國中山大學中山紀念醫(yī)院口腔頜面外科
摘要：Mitochondrial dynamics can regulate Major Histocompatibility Complex (MHC)-I antigen expression by cancer cells and their immunogenicity in mice and in patients with malignancies. A crucial role in the mitochondrial fragmentation connection with immunogenicity is played by the IRE1α-XBP-1s axis. XBP-1s is a transcription factor for aminopeptidase TPP2, which inhibits MHC-I complex cell surface expression likely by degrading tumor antigen peptides. Mitochondrial fission inhibition with Mdivi-1 upregulates MHC-I expression on cancer cells and enhances the efficacy of adoptive T cell therapy in patient-derived tumor models. Therefore mitochondrial fission inhibition might provide an approach to enhance the efficacy of T cell-based immunotherapy.
Nature Communications
[IF=17.694]
文獻引用抗體：
bs-2641R;Anti-Integrin alpha 6 pAb; IF
作者單位：美國俄亥俄州克利夫蘭診所癌癥生物學系
Nature Communications
[IF=17.694]
文獻引用抗體：
bs-4573R;Anti-APOA1 pAb
作者單位：中國科學技術大學合肥國家微尺度物理科學研究中心
摘要：Nanoparticle elasticity is crucial in nanoparticles’ physiological fate, but how this occurs is largely unknown. Using core-shell nanoparticles with a same PEGylated lipid bilayer shell yet cores differing in elasticity (45 kPa – 760 MPa) as models, we isolate the effects of nanoparticle elasticity from those of other physiochemical parameters and, using mouse models, observe a non-monotonic relationship of systemic circulation lifetime versus nanoparticle elasticity. Incubating our nanoparticles in mouse plasma provides protein coronas varying non-monotonically in composition depending on nanoparticle elasticity. Particularly, apolipoprotein A-I (ApoA1) is the only protein whose relative abundance in corona strongly correlates with our nanoparticles’ blood clearance lifetime. Notably, similar results are observed when above nanoparticles’ PEGylated lipid bilayer shell is changed to be non-PEGylated. This work unveils the mechanisms by which nanoparticle elasticity affects nanoparticles’ physiological fate and suggests nanoparticle elasticity as a readily tunable parameter in future rational exploiting of protein corona.
Genome Medicine [IF=15.266]
文獻引用抗體：bs-5720R
Anti-GDF10 pAb; IF
摘要：Background
Synovial fibroblasts (SFs) are specialized cells of the synovium that provide nutrients and lubricants for the proper function of diarthrodial joints. Recent evidence appreciates the contribution of SF heterogeneity in arthritic pathologies. However, the normal SF profiles and the molecular networks that govern the transition from homeostatic to arthritic SF heterogeneity remain poorly defined.
Methods
We applied a combined analysis of single-cell (sc) transcriptomes and epigenomes (scRNA-seq and scATAC-seq) to SFs derived from na?ve and hTNFtg mice (mice that overexpress human TNF, a murine model for rheumatoid arthritis), by employing the Seurat and ArchR packages...
Science Advances [IF=14.957]
文獻引用抗體：
bs-10232R; Anti-CD93 pAb
作者單位：第四軍醫(yī)大學口腔醫(yī)學院口腔頜面外科、軍事口腔醫(yī)學國家重點實驗室、國家口腔疾病臨床研究中心、陜西省口腔醫(yī)學重點實驗室
