產(chǎn)品編號(hào) | bs-37050R-BF647 |
英文名稱1 | Rabbit Anti-Vapreotide, Acetate/BF647 Conjugated antibody |
中文名稱 | BF647標(biāo)記的醋酸伐普肽抗體 |
別 名 | 103222-11-3 |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢價(jià) |
說(shuō) 明 書(shū) | 100ul |
產(chǎn)品類型 | 小分子抗體 |
研究領(lǐng)域 | 心血管 免疫學(xué) |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated Vapreotide, Acetate |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4. |
保存條件 | Store at -20 °C for one year. |
產(chǎn)品介紹 |
background: Vapreotide (Sanvar) is a synthetic somatostatin analog. It is used in the treatment of esophageal variceal bleeding in patients with cirrhotic liver disease and AIDS-related diarrhea. Function: Vapreotide attenuates SP-triggered intracellular calcium increases and NF-κB activation in a dose-dependent manner. Vapreotide also inhibits SP-induced IL-8 and MCP-1 production in HEK293-NK1R and U373MG cell lines. Vapreotide inhibits HIV-1 infection of human MDM in vitro, an effect that is reversible by SP pretreatment. In vivo: Vapreotide decreases portal pressure and blood flow of collateral circulation in rats with cirrhosis. Vapreotide administrated via the intravenous route is simple to use, with practically no contraindications and few, usually minor, side effects. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |