產(chǎn)品編號(hào) | bs-7346R-Gold |
英文名稱(chēng)1 | Rabbit Anti-Islet-1/Gold Conjugated antibody |
中文名稱(chēng) | 膠體金標(biāo)記的胰島素基因增強(qiáng)結(jié)合蛋白1抗體 |
別 名 | Insulin gene enhancer protein ISL 1; Insulin gene enhancer protein ISL-1; Insulin related protein; Isl 1; ISL LIM homeobox 1; ISL1; ISL1 transcription factor LIM homeodomain; ISL1 transcription factor, LIM/homeodomain (islet 1); ISL1 transcription factor, LIM/homeodomain; ISL1_HUMAN; Islet-1; Islet1. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢(xún)價(jià) |
說(shuō) 明 書(shū) | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 心血管 細(xì)胞生物 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 干細(xì)胞 細(xì)胞類(lèi)型標(biāo)志物 |
抗體來(lái)源 | Rabbit |
克隆類(lèi)型 | Polyclonal |
交叉反應(yīng) | Human, Rat, (predicted: Mouse, Cow, Horse, Sheep, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 39kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Islet-1 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. [provided by RefSeq, Jul 2008]. Function: Binds to one of the cis-acting domain of the insulin gene enhancer. Subcellular Location: Nucleus. Tissue Specificity: Expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain. Similarity: Contains 1 homeobox DNA-binding domain. Contains 2 LIM zinc-binding domains. Database links: Entrez Gene: 3670 Human Entrez Gene: 16392 Mouse Omim: 600366 Human SwissProt: P61371 Human SwissProt: P61372 Mouse Unigene: 505 Human Unigene: 42242 Mouse Unigene: 36202 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |