| 產(chǎn)品編號(hào) | bs-21178R-BF488 |
| 英文名稱1 | Rabbit Anti-RALGPS2/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的RALGPS2蛋白抗體 |
| 別 名 | dJ595C2.1; FLJ10244; FLJ25604; KIAA0351; Ral A exchange factor RalGPS2; Ral GEF with PH domain and SH3 binding motif 2; RALGPS 2; ras-specific guanine nucleotide-releasing factor RalGPS2. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) G蛋白信號(hào) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 65kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RALGPS2 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: RalGPS2 (Ral GEF with PH domain and SH3 binding motif 2) is a guanine nucleotide exchange factor for RalA GTPase. It is expressed in testis and brain. Function: Guanine nucleotide exchange factor for the small GTPase RALA. May be involved in cytoskeletal organization. May also be involved in the stimulation of transcription in a Ras-independent fashion (By similarity). Subunit: Interacts with the SH3 domains of GRB2 and PLCG1. Interacts with RALA. Subcellular Location: Cell Membrane and Cytoplasmic. Associates with membranes through the PH domain. DISEASE: RALGPS2 is a potential candidate gene for susceptibility to Alzheimer disease linked to 1q24. Database links: Entrez Gene: 424429 Chicken Entrez Gene: 457549 Chimpanzee Entrez Gene: 100052879 Horse Entrez Gene: 55103 Human Entrez Gene: 78255 Mouse Entrez Gene: 717165 Rhesus monkey Entrez Gene: 779506 Xenopus tropicalis Entrez Gene: 393446 Zebrafish SwissProt: Q5ZJK0 Chicken SwissProt: Q4R7W3 Cynomolgus Monkey SwissProt: Q86X27 Human SwissProt: Q9ERD6 Mouse Unigene: 632485 Human Unigene: 28376 Mouse Unigene: 224486 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
