產(chǎn)品編號(hào) | bs-21178R-Gold |
英文名稱1 | Rabbit Anti-RALGPS2/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的RALGPS2蛋白抗體 |
別 名 | dJ595C2.1; FLJ10244; FLJ25604; KIAA0351; Ral A exchange factor RalGPS2; Ral GEF with PH domain and SH3 binding motif 2; RALGPS 2; ras-specific guanine nucleotide-releasing factor RalGPS2. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說(shuō) 明 書(shū) | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) G蛋白信號(hào) |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 65kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human RALGPS2 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: RalGPS2 (Ral GEF with PH domain and SH3 binding motif 2) is a guanine nucleotide exchange factor for RalA GTPase. It is expressed in testis and brain. Function: Guanine nucleotide exchange factor for the small GTPase RALA. May be involved in cytoskeletal organization. May also be involved in the stimulation of transcription in a Ras-independent fashion (By similarity). Subunit: Interacts with the SH3 domains of GRB2 and PLCG1. Interacts with RALA. Subcellular Location: Cell Membrane and Cytoplasmic. Associates with membranes through the PH domain. DISEASE: RALGPS2 is a potential candidate gene for susceptibility to Alzheimer disease linked to 1q24. Database links: Entrez Gene: 424429 Chicken Entrez Gene: 457549 Chimpanzee Entrez Gene: 100052879 Horse Entrez Gene: 55103 Human Entrez Gene: 78255 Mouse Entrez Gene: 717165 Rhesus monkey Entrez Gene: 779506 Xenopus tropicalis Entrez Gene: 393446 Zebrafish SwissProt: Q5ZJK0 Chicken SwissProt: Q4R7W3 Cynomolgus Monkey SwissProt: Q86X27 Human SwissProt: Q9ERD6 Mouse Unigene: 632485 Human Unigene: 28376 Mouse Unigene: 224486 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |