| 產(chǎn)品編號(hào) | bs-4431R-APC |
| 英文名稱1 | Rabbit Anti-PTPN20/APC Conjugated antibody |
| 中文名稱 | APC標(biāo)記的蛋白酪氨酸磷酸酶非受體型20抗體 |
| 別 名 | bA42B19.1; hPTPN20; Protein tyrosine phosphatase non receptor type 20; PTN20_HUMAN; PTP Typ; PTP Typ; Ptpn20; PTPN20A; PTPN20B; Tyrosine-protein phosphatase non-receptor type 20. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 激酶和磷酸酶 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Rat, (predicted: Human, Mouse, Pig, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 48kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PTPN20 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: The product of this gene belongs to the family of classical tyrosine-specific protein tyrosine phosphatases. Many protein tyrosine phosphatases have been shown to regulate fundamental cellular processes. The encoded protein appears to be targeted to sites of actin polymerization. A pseudogene of this gene has been defined on chromosome 10. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014] Function: Tyrosine-protein phosphatase targeted to sites of actin polymerization in response of varied extracellular stimuli. Has tyrosine phosphatase activity towards various tyrosyl phosphorylated substrates. Subcellular Location: Nucleus. Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Colocalizes with the microtubule-organizing center and intracellular membrane compartments. Tissue Specificity: Present in many cell lines (at protein level). Widely expressed. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily. Contains 1 tyrosine-protein phosphatase domain. Database links: Entrez Gene: 26095 Human Entrez Gene: 653129 Human Omim: 610630 Human Omim: 610631 Human SwissProt: Q4JDL3 Human Unigene: 440733 Human Unigene: 499552 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
