產(chǎn)品編號(hào) | bs-4428R-Gold |
英文名稱1 | Rabbit Anti-PTPLA/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的蛋白酪氨酸磷酸酶PTPLA抗體 |
別 名 | 3-hydroxyacyl-CoA dehydratase 1; CAP; Cementum attachment protein; HACD1; HACD1_HUMAN; Protein-tyrosine phosphatase-like member A; PTPLA; RP23-334M9.1. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 32kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human PTPLA |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: The protein encoded by this gene contains a characteristic catalytic motif of the protein tyrosine phosphatases (PTPs) family. The PTP motif of this protein has the highly conserved arginine residue replaced by a proline residue; thus it may represent a distinct class of PTPs. Members of the PTP family are known to be signaling molecules that regulate a variety of cellular processes. This gene was preferentially expressed in both adult and fetal heart. A much lower expression level was detected in skeletal and smooth muscle tissues, and no expression was observed in other tissues. The tissue specific expression in the developing and adult heart suggests a role in regulating cardiac development and differentiation. [provided by RefSeq, Jul 2008] Function: Responsible for the dehydration step in very long-chain fatty acids (VLCFAs) synthesis. Subcellular Location: Endoplasmic reticulum membrane. Tissue Specificity: Highly expressed in the myocardium, and to a lesser extent in skeletal and smooth muscular tissues including those from stomach, jejunum, and bladder. Similarity: Belongs to the very long-chain fatty acids dehydratase HACD family. Database links:
Entrez Gene: 9200 Human
Entrez Gene: 30963 Mouse
Omim: 610467 Human
SwissProt: B0YJ81 Human
SwissProt:
Q9QY80 Mouse
Unigene:
114062 Human
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |