產(chǎn)品編號 | bs-7186R-Gold |
英文名稱1 | Rabbit Anti-ZNF224/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的鋅指蛋白224抗體 |
別 名 | BMZF 2; BMZF-2; BMZF2; Bone marrow zinc finger 2; KOX22; Zinc finger 2, bone marrow; Zinc finger protein 224; Zinc finger protein 233; Zinc finger protein 255; Zinc finger protein 27 (KOX 22); Zinc finger protein 27; Zinc finger protein KOX22; Zinc finger protein ZNF255; ZN224_HUMAN; ZNF224; ZNF255; ZNF27. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 轉(zhuǎn)錄調(diào)節(jié)因子 鋅指蛋白 表觀遺傳學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 82kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human ZNF224 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
Function: May be involved in transcriptional regulation as a transcriptional repressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells. Subunit: Interacts with WT1. Interacts with DEPDC1A. Subcellular Location: Nucleus. Tissue Specificity: Ubiquitous. Mainly expressed in fetal tissues. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 18 C2H2-type zinc fingers. Contains 1 KRAB domain. Database links: Entrez Gene: 7767 Human Omim: 194555 Human SwissProt: Q9NZL3 Human Unigene: 585869 Human Unigene: 744152 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |