產(chǎn)品編號(hào) | bs-12641R-BF647 |
英文名稱1 | Rabbit Anti-SMPD4/BF647 Conjugated antibody |
中文名稱 | BF647標(biāo)記的鞘磷脂磷酸二酯酶4抗體 |
別 名 | EC 3.1.4.12; EC=3.1.4.123; FLJ20297; FLJ20756; KIAA1418; NET 13; NET13; Neutral sphingomyelinase 3; Neutral sphingomyelinase III; NSMA3_HUMAN; nSMase 3; nSMase-3; nSMase3; OTTHUMP00000162391; OTTHUMP00000190862; SKNY protein; smpd4; Sphingomyelin phosphodiesterase 4; Sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase 3). |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說(shuō) 明 書 | 100ul |
研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 轉(zhuǎn)運(yùn)蛋白 |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse, (predicted: Human, Rat, Dog, Pig, Cow, Horse, Rabbit, ) |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 93kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human SMPD4 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: Sphingomyelinases (EC 3.1.4.12), such as SMPD4, catalyze the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide (Krut et al., 2006 [PubMed 16517606]).[supplied by OMIM, Mar 2008] Function: Catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide. Subunit: Associates with spliceosomes. Associates with U4/U5/U6 tri-snRNP and with U2 snRNP. Subcellular Location: Endoplasmic reticulum membrane. Golgi apparatus membrane. Tissue Specificity: Widely expressed, with highest levels in heart and skeletal muscle. Similarity: Belongs to the SMN family. Contains 1 Tudor domain. Database links: Entrez Gene: 55627 Human Entrez Gene: 77626 Mouse Omim: 610457 Human SwissProt: Q9NXE4 Human SwissProt: Q6ZPR5 Mouse Unigene: 516450 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |