產(chǎn)品編號 | bs-19751R-Gold |
英文名稱1 | Rabbit Anti-SH3BP4/Gold Conjugated antibody |
中文名稱 | 膠體金標記的SH3結(jié)構(gòu)域結(jié)合蛋白4抗體 |
別 名 | BOG25; EH binding protein; EH binding protein 10; EH-binding protein 10; EHB10; SH3 domain binding protein 4; SH3 domain-binding protein 4; SH3B4_HUMAN; sh3bp4; Transferrin receptor trafficking protein; Transferrin receptor-trafficking protein; TTP. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 細胞生物 信號轉(zhuǎn)導(dǎo) 轉(zhuǎn)運蛋白 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse, Rat, (predicted: Human, Cow, Horse, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 107kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human SH3BP4 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: This gene encodes a protein with 3 Asn-Pro-Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. This protein is involved in cargo-specific control of clathrin-mediated endocytosis, specifically controlling the internalization of a specific protein receptor. [provided by RefSeq, Jul 2008] Function: Functions in transferrin receptor internalization at the plasma membrane through a cargo-specific control of clathrin-mediated endocytosis. Subcellular Location: Membrane > clathrin-coated pit. Cytoplasmic vesicle > clathrin-coated vesicle. Nucleus. Specifically associated with transferrin receptor-containing clathrin-coated pits and clathrin-coated vesicles. May also localize to the nucleus. Tissue Specificity: Expressed in all tissues tested with higher expression in pancreas. Expressed by retinal pigment epithelial cells (at protein level). Post-translational modifications: Phosphorylated upon EGF stimulation. Phosphorylation prevents interaction with DNM2. Similarity: Contains 1 SH3 domain. Database links: Entrez Gene: 100730563 Guinea pig Entrez Gene: 100065797 Horse Entrez Gene: 23677 Human Entrez Gene: 98402 Mouse Entrez Gene: 100347097 Rabbit Omim: 605611 Human SwissProt: Q9P0V3 Human SwissProt: Q921I6 Mouse Unigene: 516777 Human Unigene: 170983 Mouse Unigene: 35396 Rat Unigene: 36062 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
1、抗體溶解方法 | |
2、抗體修復(fù)方式 | |
3、常用試劑的配制 | |
4、免疫組化操作步驟 | |
5、免疫組化問題解答 | |
6、Western Blotting 操作步驟 | |
7、Western Blotting 問題解答 | |
8、關(guān)于肽鏈的設(shè)計 | |
9、多肽的溶解與保存 | |
10、酶標抗體效價測定程序 | |